Bedford is the town where Davan and Aubrey grew up.  For much of Something Positive, Bedford was a secondary setting, only used for flashbacks, holidays, or stories that revolve around Fred, Faye, or Monette.  More recently, however, Davan and PeeJee have moved to Bedford in order to help take care of Fred, who is suffering from Alzheimer's syndrome.

Bedford is also the home of Donna and Rory Sawyer, the former being a high school classmate of Davan's, and the latter being her son.